Frequently asked questions

For general gut-brain health, we recommend 1 teaspoon of ION* Gut Support taken orally 3x/day. Optimal gut support is achieved when taken 30 minutes prior to meals because of ION* Gut Support's protective effects against gluten and glyphosate, but you can take it immediately before, with, or after a meal, (or on an empty stomach) and still receive benefit.

Results can vary with initial ION* Gut Support usage, with many customers reporting rapid and profound early results. These results are not the direct effects of the supplement itself, but instead reflect the innate process that occurs in a body as the firewall system is optimally up and running. There is a subset of individuals, however, that can experience symptoms of tiredness, headache, bloating/increased gas, or bowel changes. If you feel your client may be sensitive to the changes that can occur as their innate defenses and capacity for water/nutrient absorption are restored, we suggest a slower approach. Start with 1/8 teaspoon of ION* Gut Support daily, increasing usage slowly, as tolerated, to get to recommended label usage.

ION* Gut Support is an all-natural liquid gut health supplement that goes beyond probiotics, helping to support tight junction integrity and diversify your microbiome the natural way. It is soil derived and U.S. sourced. Its active ingredient, humic extract (from ancient soil), is naturally rich in a variety of trace minerals and amino acids. ION* Gut Support isn't bacteria; it's a family of molecules made by bacteria.

ION* Gut Support strengthens tight junction integrity at the gut lining, which protects the immune and neurologic systems and regulates the delivery of water and nutrients to the body.

As demonstrated in our peer reviewed articles, toxins like glyphosate and gluten can degrade tight junctions in the epithelial layer of the gut lining. ION* Gut Support has been shown to promote the strengthening of the gut barrier, thereby bolstering the first line of defense against everyday exposure to toxins. With a strong gut lining, both digestion and immune function are improved. Further, by acting as a carrier molecule, ION* moves nutrients into the cells where they are needed the most.

Think of ION* as an extremely intelligent transporter that works at a cellular level. ION* isn't adding anything, it's facilitating partnership.

The fulvate molecules in ION* are bacterial metabolites that chelate (bind) with minerals, amino acids, etc. to help transport them into cells where they are needed. Further, fulvate can remove waste and harmful toxins within the cell and transport them out of the body.

Fulvate can even partner with metal ions. By promoting metal bridges between molecules, it encourages electron transfer both within and across molecules which helps facilitate the communication aspect of ION*, what we refer to as "redox signaling". Encouraging cellular communication is truly profound, ultimately promoting innate cellular health. After all, a cell that can reach out and "ask" for what it needs will have an easier time getting it than a cell in isolation.

ION* can also do things like donate electrons to free radicals (acting as an antioxidant), downregulate zonulin (the protein that weakens tight junctions), and diversify your gut microbiome by supporting the structure of your gut lining (where your microbiome lives).

But the truly extraordinary thing about the "how" of ION*? It functions in all of these amazing ways inherently. ION* naturally works to give each cell what is needed and remove what is not. We have not synthesized any chemical compounds to seek out and identify what each of your cells need. In truth, we couldn't replicate this kind of inherent wisdom if we tried. Nature is the spark behind this innovative molecule. And it is as a nod to that very wisdom that we are so named, ION* Intelligence of Nature.

Currently, 80% of the population suffers from gas, bloating, indigestion, and heartburn, with a good majority stemming from poor gut health. But when you factor in inflammation that is caused by poor gut health, those are just the tip of the iceberg. Given the number of issues that chronic inflammation is responsible for, maintaining gut health is vital.

So why do we suddenly need help maintaining our gut health? To start, overprescribed antibiotics, glyphosate damage, and a lost connection with our environment. Our microbiome is not thriving as it should, and neither are we. Rather than address a specific medical condition with a narrowly-targeted supplement, ION* Gut Support takes a holistic approach and helps maintain the strength of our immune system to create an environment that supports total body and mind health.

Humic Extract (from Ancient Soil), Purified Water and Sea Salt.

Humic extract is sourced from ancient soil (roughly 60 million years old), and contains a blend of bacterial metabolites (aka, fulvate) as well as less than 1% of a variety of trace minerals and amino acids including chloride, sodium, lithium, calcium, phosphorus, sulfur, bromide, potassium, iron, antimony, zinc, copper, gold, magnesium, alanine, glycine, histidine, isoleucine, methionine, threonine, and valine.

Please note, all of the trace minerals in our humic extract are naturally occurring, well below the RDI, and not meant to be used as supplementary to any deficiencies. The truly active compound in humic extract is the fulvate, a unique family of carbon molecules with oxygen-binding sites that are produced by bacteria when they digest nutrients. These molecules are the backbone of the ION* blend, helping with critical functions like cellular and microbial communication and chelation of nutrients.

ION* Gut Support is not a prebiotic, a probiotic, or a direct source of enzymes. We need a much more diverse microbiome than one can achieve by replicating the same strands of bacteria over and over (this monoculture can happen when we take probiotics).

ION* Gut Support is unique in that it strengthens the gut lining to foster a more diverse microbiome, naturally. A strong gut lining helps to defend against environmental and foodborne toxins that harm the microbiome, causing gut and health issues.

Note: Please consult your healthcare provider concerning the addition or removal of probiotics and digestive enzymes in your personal regimen; as each person is unique, we cannot make individual recommendations.

ION* Gut Support is a balanced formula, comprised of a unique family of carbon molecules with oxygen-binding sites that are produced by bacteria when they digest nutrients. We extract our primary ingredient from ancient soil that contains humic and fulvic substances.

Fulvate (what ION* utilizes) has not been acidified like fulvic acid and exists naturally in our source material, Leonardite.

Oxygen atoms in fulvate molecules are partnered (chelated) with metal ions. Metal bridges between molecules allow electron transfer both within and across molecules which helps facilitate the communication aspect of ION*, what we refer to as redox signaling. This ability to enhance communication at the cellular level is what differentiates us from your average fulvic acid.

When fulvate is acidified, oxygen atoms in fulvic acid are bound to hydrogen instead of metals. Hydrogen does not support electron transfer between molecules and therefore may not facilitate redox signaling.

Yes, every product in the ION* suite is all natural and soil derived; the color, taste, and amount of sediment in each bottle can vary. It is neither abnormal nor harmful.

No, all of the products in the ION* suite are shelf stable and do not require refrigeration.

There are no known contraindications with ION* Gut Support. However, for maximum efficacy of all products, we do suggest separating by 30 minutes if you are taking ASEA, a thyroid medication, iodine, or a binder supplement.

Iodine is a highly-charged element that can bind to negatively-charged elements in ION* Gut Support. Also, certain "binder" supplements (clay, charcoal, and zeolites) are recommended to be taken separately from any nutrition, food, or supplements.

ION* Gut Support strengthens healthy gut membranes. This support can return expected drug absorption to normal levels and may improve bioavailability of supplements and food nutrients. If your client is on a medication that requires blood level testing to adjust the dose (such as blood thinners or seizure medications) and you are not the prescribing physician, they should discuss ION* with their doctor as they may want to get testing done within a week of starting ION* Gut Support, as you would do with a diet change or adding other mineral supplements.

None of the minerals or amino acids in ION* Gut Support are present in levels that would be considered adequate to allow ION* Gut Support to replace other standard mineral therapies, such as Lithium orotate, or your regular multi-mineral supplement, in your health management.

While we know of no contraindications during pregnancy, we would recommend consulting your healthcare provider, before continuing, or starting ION* Gut Support while pregnant or nursing.

Dietary supplements are never FDA approved. Unlike pharmaceutical drugs, dietary supplements fall under a different regulatory framework. The FDA does, however, regulate dietary supplements under the Dietary Supplement Health and Education Act of 1994 (DSHEA), and ION* adheres strictly to these guidelines.

Further, as the regulatory landscape changes, we are constantly working to stay up-to-date with industry standards.

Yes! All products in the ION* Suite are vegan, naturally gluten-free, dairy-free, soy-free, latex-free, sulfite-free, preservative-free, non-GMO, and certified glyphosate residue free. They are all produced in a facility free of allergens, including peanuts and tree nuts.

ION* Gut Support has numerous naturally occurring trace minerals and amino acids in it. We are aware of the vulnerability to some of these elements that certain individuals have. However, the concentrations of these trace minerals are far below the concentrations seen in the daily intake of a healthy plant-based diet and never in the metallic form typically associated with sensitivity. Cucumbers, for example, are high in naturally occurring aluminum.

Sensitivity to the ionic and organic minerals found in ION* Gut Support, therefore, is not common. Additionally, ION* Gut Support is sourced from plant-derived fossils and is routinely tested for contaminants. However, if your clients have an allergy to trace minerals, we recommend starting them slowly with ION* Gut Support, as detailed under "Usage Instructions". If you believe your client is experiencing an allergic reaction to ION* Gut Support, they should stop taking the product immediately, and consult their healthcare practitioner.

As ION* Gut Support begins to strengthen the tight junctions in the gut lining, it is not uncommon to experience mild, temporary side effects such as constipation as full hydration is promoted. In these cases, the first and best response is to increase consumption of water and herbal teas. It may also be beneficial to take a slower approach. See under "Usage Instructions" for sensitive individuals.

"Detoxing"

The clinical spectrum of signs and symptoms that have been attributed to the word "detox" are vast. If we consider the full term, "detoxification", we can bring some clarity to the process. The need to remove toxins is part of the body's natural defense, and a healthy body has vast mechanisms for toxin removal.

Many people starting ION* Gut Support have noted almost immediate signs of toxin clearance from the body. Urine, sweat, breath, and skin in the case of mineral foot baths, can all reveal toxin clearance. This is the result of the extremely rapid changes in tight junction integrity as ION* Gut Support promotes functional tight junctions in the gut, blood vessels, kidney tubules, etc.

ION* does not detox your system in the way that most products marketed as a detox do. Instead, ION* Gut Support provides a gentle, constant cellular detox that chelates to metals and other unwanted cellular waste and helps to remove them from the body. The body's natural systems, once back online with intelligent membranes, produce all the natural detoxification pathways. If tight junction restoration throughout the system is the reason for the mobilization of toxins and subsequent removal (detoxification) from the body, there is no redistribution of the toxin to other tissues. The toxins are instead trafficked to appropriate clearance sites of urine, breath, and sweat.

Your clients should take ION* Gut Support as long as they are exposed to the environmental factors known to impact the tight junctions in the gut lining, including gluten, glyphosate, and antibiotics. Organic, non-GMO, and gluten-free foods are great. However, avoiding exposure to glyphosate is the bigger challenge, as it has been shown to be contaminating even our rainwater.

So why do we suddenly need help maintaining our gut health? To start, overprescribed antibiotics, glyphosate damage, and a lost connection with our environment. Our microbiome is not thriving as it should, and neither are we. Soil depletion has led to a loss of nutrients in our foods, and commonly used herbicides like glyphosate are wreaking havoc on our health. Thus, toxin protection and optimal nutrient absorption are essential. By acting as a carrier molecule, ION* helps to move nutrients from your daily meals into the cells, and move toxins out of the body.

Rather than address a specific medical condition with a narrowly targeted supplement, ION* Gut Support takes a holistic approach to wellness, helping to maintain the strength of our digestive and immune systems for whole-body health.

Through third-party stability testing, we know that ION* Gut Support is safe and efficacious for up to 3 years.

Tight junctions are the seals between cells which help to create a defensive barrier in the epithelial layer of your gut lining. They function to keep toxins and foreign particles out of the bloodstream while also allowing nutrients to enter. Tight junction integrity is at the foundation of health.

Tight junctions are protected by the carbon and mineral metabolites of bacterial digestion. When the intestinal bacteria are balanced and thriving, this matrix of metabolites produces a strong enzyme defense system that protects the tight junctions from the toxin zonulin.

Over the last sixty years, there has been a steady loss of biodiversity in our bowel bacterial ecosystem. Factory farming, processed foods, and widespread antibiotic use have all played major roles in this decline. However, the most potent of triggers for zonulin impact at the gut barrier is glyphosate, the most commonly used herbicide. Gluten is the most potent of naturally occurring triggers for zonulin production in our modern diet.

ION* Gut Support functions as the answer to glyphosate and gluten impact at the gut lining by promoting increases in production of the enzymes that break down zonulin and thereby strengthen tight junctions.

Recent science has called the gut our "second brain," or "Enteric Nervous System" (ENS). It consists of two thin layers of more than 100 million nerve cells that line our gastrointestinal tract, from our sinuses all the way to our rectum, and serves as a vast communication network. We now know that the majority of neurotransmitters, or "chemical messengers," such as serotonin and dopamine, are made in our gut lining, with very little being made in the brain comparatively. However, the production of these chemical messengers is dependent on the right bacteria, fungi, and even parasites and viruses (collectively known as the microbiome), being present in our gut.

Glyphosate is the active ingredient in the most commonly used weed killers, including Roundup. These weed killers are used broadly in agriculture and found in varying quantities throughout our environment. The volume of usage of this herbicide has led to reports of significant levels of glyphosate in water, air, rainfall, and even human breast milk. The World Health Organization classified glyphosate as a "probable human carcinogen", and it is implicated in a wide variety of human health disorders.

ION* Gut Support functions as a response to glyphosate and gluten impact by improving the gut lining's ability to keep out these detrimental elements and promoting increases in production of beneficial enzymes. ION* Gut Support promotes a healthy "firewall" in the gut and blood-brain barrier, to support a beneficial shift in the gut ecosystem as well as normal immune function. ION* Gut Support improves gut resilience to glyphosate within 16 minutes.

In compliance with California's Prop 65 legislation, we test ION* for levels of mercury, lead, arsenic, and cadmium. It is important to note, however, that metals are found naturally in soil. In fact, there are heavy metals everywhere, from the air we breathe to the food we eat. For example, candy can have 100-6000 ppm lead, and root vegetables can easily have about 2 ppm lead. Fish bodies can have 1-4 ppm mercury and rice in the US can have over 0.5 ppm arsenic.

Our limits are set low, and we typically see levels 10-fold less than those limits. The result? You would typically need to consume 100x the recommended dose to approach the Prop 65 No Significant Risk level.

Please note: 1 ppm = 1 ug/ml

Mist ION* Skin Support on face, neck and chest twice daily. Use before applying other skin products, before and after sun exposure, or wherever your skin needs support. For best results, allow to dry or massage into skin before applying other skincare products.

If you feel your client may be sensitive to the trace minerals or humic extract found in ION* Skin Support, please patch test to ensure there is no reaction. If your client experiences any adverse reactions from using ION* Skin Support, recommend they discontinue use and please contact our Customer Support Team for additional support.

ION* Skin Support is an all-natural, soil-derived spray utilizing our innovative Terrahydrite® blend, combined with various bio-available minerals including Silicon as Monomethylsilanetriol, Zinc Gluconate, Copper Gluconate, and Magnesium Citrate. ION* Skin Support is scientifically proven to strengthen your barrier against toxins, support a healthy response to the sun, and improve hydration. It is microbiome-friendly as well as fragrance and dye-free.

ION* Skin Support is designed to support skin function as a barrier and as a balanced terrain for your microbiome. By supporting a terrain that can host hundreds of millions of beneficial microbiota, you can help foster your innate gut-brain-skin connection.

ION* Skin Support also helps defend against toxins by maintaining the tight junctions in the skin, supports a healthy response to the sun by lowering the amount of reactive oxygen species that result from exposure to UVB rays, and improves overall skin hydration by supporting your microbiome.

In addition to the humic extract blend utilized in our Gut Support formula, ION* Skin Support includes bioavailable Silicon as Monomethylsilanetriol, Zinc Gluconate, Copper Gluconate, and Magnesium Citrate. It is a synergistic blend specially formulated for keratinocytes, the primary cells which form the skin barrier.

They may notice an improvement in texture, elasticity, hydration, smoothness, or circulation and/or a reduction in redness after a few weeks of regular ION* Skin Support use.

Further, when your skin functions properly, it supports many other functions, as the skin is deeply connected to the hormone system, the immune system, and the nervous system. Because of these connections, you and your clients may notice benefits that go far beyond what was expected.

Because the skin is influenced by the state of the nervous and endocrine systems as well as the microbiome, the cause of skin conditions is quite complex and depends on the individual.

While we cannot make claims related to specific skin conditions, we suggest applying ION* Skin Support to your external barrier as well as taking ION* Gut Support to promote immune health inside and out.

Many skin conditions are an immune response to environmental toxins or insults (like UV rays) resulting in inflammation. ION* Gut Support bolsters your immune system by improving intracellular communication. ION* Skin Support strengthens the barrier of epithelial cells that separates you from the outside world, improving your body's ability to respond to environmental toxins and/or damaging levels of UV rays.

Everyone's skin is different, specifically for those with sensitive skin, it is recommended to patch test to ensure your client does not experience any adverse skin reactions.

Good spot/patch testing practices:

• Test on freshly cleansed skin.
• Test on your neck or inner arm.
• Test one new skin product at a time.
• Test for four or more days to ensure you do not develop a hypersensitivity reaction.

We recommend using ION* Skin Support within 2 years.

No, all products in the ION* suite are shelf stable and do not require refrigeration.

With ION* supporting the body's barrier protection from UVB rays and environmental toxins, it should be used as long as those damaging elements are present. As ION* is a water-based product, it is quickly absorbed; use twice daily as instructed.

Noticeable changes in the skin vary and are dependent on an individual's overall health, skin health, and their personal awareness of its appearance. Irritated or inflamed areas of the skin are where an individual will most likely notice the impact of ION* Skin Support first. Skin with callouses, or thick layers of skin, will likely be where noticeable changes will take the longest. Noticeable changes will also vary with skin age and exposure to sunlight and toxins.

This can be a difficult question to answer with usage varying widely. However, based on an average use regimen for one person, an 8oz spray bottle should last about 10 weeks and a 3.4oz bottle should last roughly 1 month.

Applying ION* Skin Support substantially more than twice daily may result in some irritation. Further, it's important to remember that more is not necessarily better. We have no reason to believe that you will receive any more benefit from overuse of ION* Skin Support. Thorough coverage, twice daily, will provide the support your skin needs.

You can apply makeup or lotions immediately following use of ION* Skin Support. We recommend either letting it dry naturally or gently patting dry and then applying other products.

We cannot say at this time. We will, however, be carrying out studies to validate ION* Skin Support's effect on wrinkles and signs of aging. Stay tuned!

What we know now is that ION* Gut Support, our flagship liquid mineral supplement, has been shown to increase lysine production, which is critical to the formation of collagen. Collagen is key in helping to promote skin elasticity and strength.

No. ION* Skin Support does not physically block UV rays or chemically alter our response to them. It should not be used as a sunscreen.

With daily use, however, ION* will help to balance the microbiome which supports healthy lipids (natural oils and waxes), making our skin less vulnerable to damaging rays. ION* Skin Support helps to achieve a balanced state of ROS which means less ROS is acting to damage and kill cells.

No, we do not recommend ION* Skin Support for babies due their highly sensitive skin.

Shake Well. Ideal application is by syringe (no needle) in the corner of mouth (not squirted in – but gradually dispensed). You can also pour ION* Gut Support For Pets into one-quarter cup of dechlorinated water.

Pets can drink ION* Gut Support For Pets before, during, or after a meal and still receive benefit. If you feed twice daily, you can split the following doses in half and provide twice daily.

For pet weight:
<20 lbs: 1 tsp (5 ml) daily
21 lbs to 100 lbs: 2 tsp (10 ml) daily
>101 lbs: 1 Tbsp (15 ml) daily

Starting with 1/8 teaspoon of ION* Gut Support For Pets, once a day, can be a good introduction. Double the usage weekly until your pet is fully benefitting from the recommended usage for their weight category. Give at mealtime or twice daily in one-quarter cup of dechlorinated water.

Please note: These usage schedules are for canines and felines. ION* Gut Support For Pets has not been tested in the equine environment.

ION* Gut Support For Pets is a liquid supplement that supplies the first line of defense against everyday exposure to environmental and food-borne toxins. It is an all-natural humic extract derived from ancient soil.

The gut lining is a barrier working to protect your pet from toxic substances such as glyphosate, gluten, and other foreign particles. But just as importantly, it functions to allow the passage of beneficial nutrients. Preserving the integrity of this barrier is key to health. Instead of feeding the microbiome with various bacterial strains, as you would get from a probiotic, ION* Gut Support For Pets works via redox signaling to maintain tight junction integrity in the epithelial layer of the gut lining.

ION* facilitates nutrient absorption, promotes kidney health, and helps with the inflammatory response promoting immune function and alleviating environmental allergy sensitivities.

Yes! Our manufacturing and quality control teams adhere to all the FDA's current Good Manufacturing Practices (cGMPs), and do regular testing on ION* Gut Support For Pets for bacterial contamination, heavy metals, and overall product composition.

Further, third-party testing has shown ION* to be non-toxic on sensitive kidney cells, even at very high concentrations.

ION* Gut Support For Pets is specially formulated for canines and felines and includes silicon. Silicon, not commonly found in pet food, supports structure in the body from the cellular level to the muscular-skeletal level. It is an essential element for healthy connective tissues, especially in the bone and cartilage of animals.

If an existing practitioner refers another practitioner to become an ION* reseller^†, then both parties will receive a $100 credit towards their next ION* product purchase.

^†The new practitioner must complete the application, be approved by our sales team, and place their opening order for either party to receive a $100 credit.

You will earn a $100 credit for each referral that signs up for a new wholesale account with ION*!

Absolutely, we hope you will share the power of ION* with all your colleagues!

Yes! You can use as many referral credits as you have available on your next purchase of ION* products.

Currently our website cannot automatically apply a referral credit onto your order. Please contact us to help you use your referral credit!

Unfortunately, our Direct to Consumer (DTC) Referral Program can only apply to orders placed on the DTC Site. We cannot apply any DTC Referral Program credits to your next wholesale order.

Standard shipping rate for wholesale orders is $15 for orders under $200, and free over $200.

Most orders are shipped through our preferred carriers, FedEx and UPS.

No, we do not ship orders to freight forwarding addresses or to PO Boxes.

Product will ship within one week of order confirmation. If there are any backorders, production or manufacturing issue or other shipping delays, our team will alert you immediately. You can find a copy of our wholesale shipping policy in your reseller agreement.

A tracking number will automatically be emailed to the email address used to place the order when it is picked up by the carrier.

If you cannot find your tracking number, please check your spam folder.

If you have any questions, please email us at info@intelligenceofnature.com. We’d be happy to check on your order for you.

Yes, we can provide a quote for expedited shipping upon request. Please reach out to our team to request a quote.

We want you to have an incredible experience ordering from us. If your package arrives damaged, please email us immediately at info@intelligenceofnature.com. Please include an image of the damage so that we can expedite your replacement.

We will honor our 100%, 60-day, money-back guarantee by crediting your wholesale account for product you refund to your customers. First purchase, one bottle only, and within 60 days of purchase. Please contact us with any questions.

You can get started by filling out our Wholesale Interest Form! A team member will be in touch once they receive your inquiry.

Yes, we offer prerecorded, self-led, and group or 1:1 training calls to support our partners. Please reach out to us at info@intelligenceofnature.com to inquire about availability.

Unfortunately, at this time we do not have the capacity to offer single bottles at a wholesale discount. We are currently partnering with Wholescripts, Fullscripts, and Emerson to support practitioner dropship needs.

These two programs have different applications / vetting processes to qualify. Our Affiliate program is commission based and utilizes a discount code through a social media platform for the audience to add at checkout on our DTC site.

Yes! You can sell ION* on your website. All partners must adhere to the terms of our agreement and MAP policy. Don’t forget to utilize our Digital Media Kits to promote ION* products with all our digital tools.

No, our Resellers cannot sell or distribute Products to any other wholesalers, distributors, or other resellers; through third party websites (e.g Amazon); or by using drop-shipping / freight forwarders or any other person that intends to re-sell the Products.

Also, our Authorized Resellers cannot either directly or indirectly through third parties, sell or distribute products through auction services (e.g eBay), multilevel marketing, pyramid selling, network marketing, referral marketing, or similar selling practices.

No, our domestic resellers are only permitted to sell and ship ION* products within the continental US.

Residents in Australia and New Zealand can order from our consumer site, intelligenceofnature.com. If your clients reside in the UK, you can direct them to purchase from our UK Distributor at
Web: https://uk.intelligenceofnature.com/
Email: uk.info@intelligenceofnature.com
Phone: 0330-223-5646

For all other countries, please direct your clients to iHerb to see if ION* can be shipped to their location.

We are here to support you in whatever way is most convenient for you. Login to your account at reseller.intelligenceofnature.com to order at your convenience. Prefer to order by email? Please email your orders to info@intelligenceofnature.com. If you prefer to order by phone, or if you have any questions and would like to speak to someone, you can reach us at 844-432-5488.